Business news

Design and Safety Considerations for Clinical Trials Involving Ibogaine Drug Products; Request for Information

The Food and Drug Administration (FDA or the Agency) is describing the approaches it is considering for the design of early- phase clinical trials of ibogaine drug products and is opening a public docket to receive comments. The Department of Health and Human Services (HHS) is funding clinical development of ibogaine, and the first federally supported trials are expected to study ibogaine in adults with opioid use disorder (OUD) and adults with post-traumatic stress disorder (PTSD). FDA is building on the guidance for industry entitled "Psychedelic Drugs: Considerations for Clinical Investigations" by seeking comments, data, and information from the public on protocol elements relevant to ibogaine development--including dose selection and escalation, care setting, safety monitoring, eligibility criteria, stopping rules, and safety oversight, in part, because the Federal Government is funding work in this area. FDA will consider all information provided in response to this Request for Information (RFI) to inform whether and how these specific elements should be considered in its review of Investigational New Drug Applications (INDs) involving ibogaine.

Oct 6, 2026 · 1 min read

Reef Fish Fishery of the Gulf of America; Amendment 62

NMFS issues regulations to implement management measures described in Amendment 62 to the Fishery Management Plan for the Reef Fish Resources of the Gulf (FMP), as prepared and submitted by the Gulf Council (Council). This final rule and Amendment 62 revise the catch limits and sector allocations for Gulf of America (Gulf) red grouper, based on the best scientific information available. Additionally, this final rule removes the shallow-water grouper (SWG) recreational seasonal closure, from February 1 through March 31, in Gulf Federal waters seaward of the 20-fathom boundary.

Oct 6, 2026 · 1 min read

Transparency in Coverage

These final rules set forth requirements that amend the regulations under the Public Health Service Act, the Employee Retirement Income Security Act of 1974, and the Internal Revenue Code regarding price transparency reporting requirements for non- grandfathered group health plans and health insurance issuers offering non-grandfathered group and individual health insurance coverage. Specifically, these final rules are intended to improve the standardization, accuracy, and accessibility of public pricing disclosures in line with the goals of Executive Order 14221, "Making America Healthy Again by Empowering Patients With Clear, Accurate, and Actionable Healthcare Pricing Information." With respect to the In- network Rate and out-of-network Allowed Amount machine-readable files, these final rules aim to achieve these goals by adding new contextual files and additional data elements like product type, provider network name, and provider network identifier; changing the reporting level for aggregation of data; removing in-network rates for unlikely provider- to-service mappings; increasing the reporting period and lowering the claims threshold for out-of-network historical data; and reducing the reporting cadence. These final rules also aim to improve the findability of all publicly disclosed machine-readable files required under the Transparency in Coverage rules, including the prescription drug file, by requiring a text file containing contact information for the files, and a footer with website URLs. These final rules also require pricing information that is made available through an online consumer tool and on paper (upon request), to also be made available by phone, and establish that the satisfaction of such requirement also satisfies the requirements of section 114 of the No Surprises Act (including for grandfathered group health plans and health insurance issuers offering grandfathered group and individual health insurance coverage that are not otherwi...

Oct 6, 2026 · 2 min read

Adoption of Updated EDGAR Filer Manual

The Securities and Exchange Commission ("Commission") is adopting amendments to Volume II of the Electronic Data Gathering, Analysis, and Retrieval system Filer Manual ("EDGAR Filer Manual" or "Filer Manual") and related rules and forms. EDGAR Release 26.3 will be deployed in the EDGAR system on September 14, 2026.

Oct 6, 2026 · 1 min read

Adviser and Regulated Fund Custody Rules; Crypto Custody Rules

The Securities and Exchange Commission (the "Commission" or the "SEC") is proposing new custody rules under the Investment Company Act of 1940 (the "Investment Company Act") and amendments to related reporting and recordkeeping requirements to address how regulated investment companies may custody crypto securities and similar investments, and amendments to the custody rule and related reporting and recordkeeping rules under the Investment Advisers Act of 1940 (the "Advisers Act") to address how registered investment advisers may custody client crypto funds and securities. We are also proposing to amend the current custody rules to modernize their requirements, to better address current industry practices and feedback, and to implement certain conforming amendments. We are also proposing amendments to the recordkeeping rules under the Investment Company Act and Advisers Act related to these proposed modernization amendments to the custody rules. Additionally, we are proposing to redesignate the custody rule under the Advisers Act and to make corresponding amendments to Form ADV and Form ADV-E for registered investment advisers to reflect the Advisers Act custody rule redesignation. We are also proposing amendments to Form ADV for registered investment advisers and Form N-CEN for regulated investment companies and to improve the quality of public disclosures made on these forms. We are also proposing to add new questions to Form ADV and Form N-CEN related to tokenized private funds and regulated investment company shares, respectively.

Oct 6, 2026 · 2 min read

Modification of Class E Airspace; Gunnison-Crested Butte Regional Airport, Gunnison, CO

This action proposes to modify the Class E airspace designated as a surface area, the Class E airspace area designated as an extension to a Class E surface area, and the Class E airspace area extending upward from 700 feet above the surface at Gunnison-Crested Butte Regional Airport, Gunnison, CO. These actions would support the safety and management of instrument flight rules (IFR) operations at the airport.

Oct 6, 2026 · 1 min read

Investment Adviser Performance-Based Compensation Modernization

The Securities and Exchange Commission (the "Commission") is proposing to amend the rule under the Investment Advisers Act of 1940 that provides an exemption from the statutory prohibition on registered investment advisers receiving compensation on the basis of a share of capital gains in or capital appreciation of an advisory client's account. Specifically, the proposed amendments would expand the ability of investment advisers to receive this compensation from clients that are registered management investment companies and business development companies (collectively, "regulated funds"), subject to certain conditions. The proposal would relatedly amend certain regulated fund registration and reporting forms to require separate disclosure of all performance-based compensation paid by regulated funds to their investment adviser. The proposed rule amendments would also allow investment advisers to receive this compensation from additional clients by revising the rule's "qualified client" definition to include investors that meet the "accredited investor" definition in Regulation D under the Securities Act of 1933. The proposal would relatedly make conforming amendments to certain other rules under the Investment Advisers Act of 1940 whose provisions reference the "qualified client" definition.

Oct 6, 2026 · 1 min read

Security Zone; Patapsco River, Baltimore, MD

The Coast Guard is establishing a temporary security zone for certain navigable waters of the Patapsco River. The security zone is needed to protect persons, including those under the protection of the United States Secret Service (USSS), and property from terrorist acts and incidents and to prevent terrorist acts or incidents during a high- ranking public official visit. Entry of vessels or persons into this zone is prohibited unless specifically authorized by the Captain of the Port, Sector Maryland-National Capital Region or a designated representative.

Oct 6, 2026 · 1 min read

Safety Zone; Red Bull Flugtag, Intercoastal Waterway, Biscayne Bay, Miami, FL

The Coast Guard is proposing to establish a temporary safety zone for certain navigable waters on the Intercoastal Waterway portion of Biscayne Bay in Miami, FL. The safety zone is needed to protect spectators, vessels, and the marine environment from potential hazards associated with event proceedings. This proposed rulemaking would prohibit persons and vessels from being in the safety zone unless specifically authorized by the Captain of the Port, Sector Miami. We invite your comments on this proposed rulemaking.

Oct 6, 2026 · 1 min read

Eliminating Obsolete Regulations Related to the 911 Grant Program

In this action, NTIA and NHTSA are removing regulations related to the 911 Grant Program because the program is no longer active and there have been no new appropriations to revive or extend it. This removal is intended to eliminate obsolete regulatory language, ensure that the Code of Federal Regulations is accurate and up-to-date, and minimize the risk of confusion regarding the availability of grant funds.

Oct 6, 2026 · 1 min read

Agency Information Collection Activities; Court-Ordered Refunds Under the International Emergency Economic Powers Act Worksheet

The Department of Homeland Security, U.S. Customs and Border Protection (CBP) will be submitting the following information collection request to the Office of Management and Budget (OMB) for review and approval in accordance with the Paperwork Reduction Act of 1995 (PRA). The information collection is published in the Federal Register to obtain comments from the public and affected agencies.

Oct 3, 2026 · 1 min read

Notice To Reestablish the Transit Advisory Committee for Safety Charter

The Federal Transit Administration (FTA) announces the reestablishment of the charter of the Transit Advisory Committee for Safety (TRACS). The previous TRACS charter expired on February 2, 2026. The U.S. Department of Transportation (DOT) and FTA are committed to ensuring the safety of the Nation's public transportation systems and reducing safety risks to both riders and transit workers. Accordingly, the Secretary of Transportation (Secretary) has determined that reestablishing TRACS is necessary and in the public interest.

Oct 3, 2026 · 1 min read